R&D Overview

Our Research Institute is always trying to take a leading edge for novel biotechnology development, one of core milestones to be the most outstanding pharmaceutical organization.

Since 1972
Established in 1972 for the first time in Korean Pharmaceutical Inducstry

Chong Kun Dang Central Research Institute, established in 1972 for the first time in Korean Pharmaceutical Industry, had been researching on fermentation, synthesis & biotechnology and was independently reorganized as CKD BiO Research Institute in November, 2001, as per the spin-off from “Chong Kun Dang Corp.”. We have been leading the localization of API production on a basis of advanced technologies, experiences & know-hows, accumulated over 40 years and every single day, we are putting our utmost passion & efforts to move towards healthier future. In the year of 1968, Chloramphenicol, developed via our own process & technology, was approved by US FDA for the first time in Korea and our activities have been recognized globally with numerous awards placed such as “Korean Good Technology Mark”, “Chang Eun Technology Award”, “Excellent Export Product”, “KOITA’s Advanced Technology Center” and etc. We are devoted to R&D using fermentation, biotechnology and organic synthesis technologies in order to secure a mass production system of APIs for improving quality of life and treating obstinate diseases, such as diabetes & hyperlipidemia. With our excellent specialists & technologies, we are committed to making every possible effort to develop APIs with outstanding efficacies and eco-friendly manufacturing process.

Fermentation Research

Conduct researches on microbial screening, strain improvement, fermentation optimization and high-yield bioconversion technologies for the targeted materials.

Focuses on the fields of

Strain improvement

  • - Classical Mutation & Selection : HTS system
  • - Genome shuffling : Cell fusion
  • - Metabolic engineering : Omics technology

Fermentation condition optimization

scale-up process development

High-yield bioconversion process development

Probiotics Research

Conduct researches on health beneficial LAB (lactic acid bacteria) screening, culture condition optimization, efficacy v​erification and coating technologies. Develop manufacturing process to commercialize ‘listed type’ and ‘individual recognition type’ probiotics improved productivity and stability.

Focuses on the fields of

Health beneficial microorganism screening & isolation

Culture condition optimization & manufacture

Coating technique for increasing stability

Development of individual recognition type probiotics

Purification and Chemical Synthesis Research

Conduct researches on recovering the targeted bioactive substance from microbial culture broth, purification process optimization, development of identification methods for spectral structure analysis, and identification & separation of impurities. Develop semi-synthetic, chemical synthetic process for producing useful substance.

Focuses on the fields of

Purification & isolation

  • - Column chromatography
  • - Impurity control & separation
  • - Recovery process develop

Synthesis & Semi-synthesis process development

Improvement of reactant & catalyst, Analytical method development